منابع مشابه
Inhalation exposure of animals.
Relative advantages and disadvantages and important design criteria for various exposure methods are presented. Five types of exposures are discussed: whole-body chambers, head-only exposures, nose or mouth-only methods, lung-only exposures, and partial-lung exposures. Design considerations covered include: air cleaning and conditioning; construction materials; losses of exposure materials; eve...
متن کاملToxic effects of combined exposure to toluene and m-xylene in animals. III. Subchronic inhalation study.
Effects of combined exposure to toluene and m-xylene in the conditions of subchronic inhalation experiments in rats were examined. Rats were exposed to vapours of individual solvents and their 1:1 mixture at concentrations of 1000 ppm or 100 ppm, 6 h/day, 5 days/week, for 3 or 6 months, respectively. In rats exposed for 3 or 6 months to toluene, m-xylene and their mixtures (1:1) at concentratio...
متن کاملInhalation exposure system used for acute and repeated-dose methyl isocyanate exposures of laboratory animals.
Laboratory animals were exposed by inhalation for 2 hr/day (acute) or 6 hr/day (four consecutive days, repeated dose) to methyl isocyanate (MIC). Exposures were conducted in stainless steel and glass inhalation exposure chambers placed in stainless steel, wire mesh cages. MIC was delivered with nitrogen via stainless steel and Teflon supply lines. Chamber concentrations ranged from 0 to 60 ppm ...
متن کاملInhalation exposure methodology.
Modern man is being confronted with an ever-increasing inventory of potentially toxic airborne substances. Exposures to these atmospheric contaminants occur in residential and commercial settings, as well as in the workplace. In order to study the toxicity of such materials, a special technology relating to inhalation exposure systems has evolved. The purpose of this paper is to provide a descr...
متن کاملConstruction of an exposure chamber for animals and its use for inhalation exposure to welding fumes and gases.
An inhalation exposure system, consisting of an inhalation chamber and an generating and feeding device for welding fumes and gases with a welding robot, was constructed and examined for its application to experimental toxicology for ventilatory responses of conscious rats to welding fumes and gases. The exposure system allowed an inhalation of fresh welding fumes and gases, and could supply ai...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1976
ISSN: 0091-6765
DOI: 10.2307/3428580